Past Webinars

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Wednesday, March 22

Immunohistochemistry and Immunofluorescence (IHCIF) Course Preview

Synthetic Antigen Gels: Quantifiable Controls for Immunohistochemistry
Frank Peale, MD, PhD, Distinguish Pathologist, Genentech

Breaking Down Tissue: Quantitative Tissue Analysis
Amber Ortiz, PhD, Senior Image Scientist at Indica Labs

Wednesday, February 22, 12:00pm eastern

100 years with Insulin. Contribution of histochemistry and microscopy to the study of insulin-secreting beta-cell

A microscopic look to the human pancreas and the pathogenesis of type 1 diabetes:
what have we learned? 
Teresa  Rodriquez-Calvo, Institute of Diabetes Research, Helmholtz Munich,
Munchen, Germany                     
Combining high-content imaging and human islet microtissues to study beta-cell biology and function
Alexandra Title, InSphero AG, Switzerland
Using immunomarkers to study beta-cell heterogeneity and dedifferentiation in animal models
Iuliana Popescu, Barnstable Brown Diabetes Research Center

Wednesday, January 25

Highlights from the Prague International Congress of Histochemistry and Cytochemistry

Multiscale Imaging of tumor targeted drug delivery,
Margarida Barroso, PhD, Albany Medical College
Histochemistry as a Tool for Student–led and Collaborative Neuroscience Research,
Joe Cheatwood, PhD, Southern Illinois University School of Medicine

Wednesday, January 11

Role of vWf-ADAMTS13 homeostasis in microthrombi formation and immunothrombosis; implications in diabetes

Roberto Mota-Alvidrez, MD, MS, University of Pittsburgh


Wednesday, December 7, 12:00pm eastern

Goal Oriented Webinar: The 3 Most Important Questions

Invited Speaker, A. Sally Davis, DVM, PhD, DACVP, DACVM is a member of both the Histochemical Society and the American Society of Investigative Pathology. Throughout her career she has been involved with the development of scientists as whole persons. Recently, she completed her Life Coach Certification with Evercoach by Mindvalley. She is passionate about coaching fellow scientists in groups and individually.


 October 26, 12:00pm US EDT 

Family Life Balance in Science Careers: How to balance it all? 

Panelist from HCS, ASIP and ASMB answered questions on this very important topic.

October 12, 2022: Awardee Highlights #4

Eva Rothenberger, "Dual COX-2/sEH inhibition enhances immunotherapy and chemotherapy to induce bladder cancer regression"
Kristen  Engevik, "HOSTile Takeover: exploitation of host responses in rotavirus pathogenesis"
Abigail Kelly, “Targeting nutrition via bioactive lipids enhances immunotherapy in cancer”




July 13, 2022: Transcriptional Control of Tissue Damage - Awardee Talk #3

IL-6 signaling is required for LPS-induced barrier function loss, Shuhan Lu, Albany Medical College
The Interplay Between Enteric Tuft Cell Responses and Giardia Colonization, Olivia Sosnowski, University of Calgary
Knockdown of p16INK4A Reduces Hepatic Steatosis, Senescence and Ameliorates Non-Alcoholic fatty liver disease phenotypes in High Fat Diet-Fed Mice, Debjyoti Kundu, Indiana University School of Medicine

July 27, 2022: Career Options in Science - Industry vs. Academia

Moderators:  Daisy Shu, PhD, Schepens Eye Research Institute, and Vik Meadows, PhD, Rutgers University
Panelists for this session were: Robin Lorenz, Genentech; Paul Goodwin, Cytiva, and Andrew Leask, University of Saskatchewan

June 29, 2022: Navigating to and through Mid-career in Academic Science

Panelists include:

Francesca Duncan, PhD, Northwestern University - The Feinberg School of Medicine
George Perry, PhD, University of Texas San Antonio
Patricia D'Amore, PhD, Harvard Medical School and The Schepens Eye Research Institute

Ashley  Brown, PhD, North Carolina State University  

 June 8, 2022: Awardee Talks #2

SARS-CoV-2 Infected Non-Human Primate Neuropathology: Inflammation and HIF-1a
Meredith Mayer, Tulane National Primate Research Center
P-glycoprotein deficiency results in intestinal developmental delay in C. elegans
Brittany Salciccioli, University of South Carolina Upstate
Sex differences in neuroinflammatory relief by NSAID nanotherapy
Brooke Deal,  Duquesne University

May 11, 2022: Awardee Talks

Mindy Engevik, Medical University of South Carolina
HCS 2022 Early Career Investigator award winner
Title: Exploring microbial interactions at the mucosal interface.
Jonathan Barra, Albany Medical College
HCS 2022 Post-Doctoral Trainee award winner
 Title: DMT1 bridges endosomes and mitochondria to modulate mitochondrial iron translocation


January 12, 2022: Rift Valley fever: A deadly zoonotic disease of ruminants and humans

Presenter: Sally Davis, DVM, PhD, DACVP, Kansas State University

ASIP co-sponsor

Description: Rift Valley fever phlebovirus (RVFV), is a mosquito-borne, zoonotic pathogen of ruminants that typically causes outbreaks in Africa and spread to the Arabian Peninsula in 2000. Pathology highlights from our study of 200 naturally infected sheep including lambs, fetuses and placentas will be discussed within the wider context of Rift Valley fever pathogenesis in ruminants as well as humans.


November 17: Seminar Series #3

More than a pretty picture: Advances in Quantitative Digital Pathology

Presenter: Charles W. Frevert, DVM, ScD, University of Washington at South Lake Union

Description: Advances in the research pathology laboratory have increased our ability to efficiently generate high-quality digital images on the expression and accumulation of mRNA, proteins, carbohydrates, signaling pathways, cells, and structures in healthy and diseased tissues. Quantitative digital pathology allows us to analyze these digital images to obtain objective, quantitative, and reproducible data suitable for statistical analysis. This webinar aims to provide an overview of the critical information required to analyze tissues stained using histochemistry, immunohistochemistry, or in situ hybridization.


October 27: Seminar Series #2The Importance of Preanalytics when Performing Immunohistochemistry

 Presenter: Stephen Hewitt, M.D., Ph.D., Center for Cancer Research, National Cancer Institute, Editor-in-Chief of The Journal of Histochemistry and Cytochemistry

Description: The quality of any assay is dependent on the quality of the specimen and reagents used to perform the assay. The Pre-analytic variable of cellular and tissue specimens have been historically under-appreciated. The competition of histomorphology versus biomolecular integrity result in complex decisions for the researcher. Dr. Hewitt will discuss the basic principles of pre-analytic quality, approaches to determining if a specimen is fit for purpose and common pitfalls based on inadequate specimen preservation.


October 13: Seminar Series #1 - Fundamentals of Microscopy: The Need for Contrast

Presenter: Paul Goodwin, Ph.D., Past-President, The Histochemical Society and Science Director, Cytiva

Description: The light microscope is one of the most ubiquitous instruments in a research laboratory yet most user lack a basic understanding of the instrument. In this lecture, Paul Goodwin will cover the basics requirements for microscopy (magnification, resolution, and contrast) and how those requirements are addressed with a special emphasis on contrast. The lecture will finish with a description of histochemistry and immunohistochemistry as ways of generating contrast with molecular specificity.

August 11: Intravital imaging to visualize age induced vasculo -epithelial changes in the liver

Featured Speaker: Tirthadipa Pradhan-Sundd, PhD, University of Pittsburgh School of Medicine


July 14: Harnessing histochemical approaches to reveal novel mechanisms of ovarian aging

Featured Speakers: Francesca Duncan, PhD,
 Farners Amargant i Riera, PhD and Elnur Babyev, MD, Northwestern University


 June 9: Tumor microenvironment multiplex immunofluorescence: an illustration of our workflow concept

Featured Speaker: Svetomir Markovic, M.D., Ph.D., Mayo Clinic
Additional Speakers: Rachel Maus PhD; and Alexey Leontovich; PhD

May 12: The Role of Myosin Vb in Maintaining Epithelial Polarity and Homeostasis

HCS 2021 New Investigator Awardee

Amy C. Engevik, Medical University of South Carolina

 April 14: Epigenetic control of vascular homeostasis and smooth muscle function

Featured Speaker: Delphine Gomez, PhD, University of Pittsburgh

February 24: Implicit Bias

An Uncomfortable Truth: Implicit Bias
Edwin J. Barea-Rodriguez, Ph.D. 
Breaking the Mold: Targeting Strategies Against Implicit Bias in Academia
Ann Caroline Fisher, M.D.

February 17: Host-proteoglycans as entry portals for ancient and emerging viruses

Invited Speaker: Sean Whelan, Department of Molecular Microbiology, Washington University in Saint Louis



 December 16: Inflammation and Heart Disease

Longitudinal In Vivo Atherosclerotic Disease Development in The apoE Deficient Zucker Rat
Roberto Mota Alvidrez, University of North Carolina at Chapel Hill
Histopathological Characterization of COVID-19-associated Cardiac Injury
Paul Hanson, University of British Columbia
SOCS3 limits pro-inflammatory signature in septic endothelium
Ramon Bossardi Ramos, Albany Medical College

November 18: Directions from the Extracellular Matrix 

Chaired by Liliana Schaefer, Allgemeine Pharmakologie und Toxikologie,
Division Nephropharmakologie, Klinikum der Goethe Universität


Preserved extracellular matrix in non-enzymatically detached cultured keratinocyte
sheets bolsters the healing effects on grafted burn wounds
Suzan Alharbi, University of Texas Medical Branch, Galveston, Texas,
and  King Abdulaziz University, Jeddah, Saudi Arabia    
Regulation of Intestinal Epithelial Intercellular Adhesion and Barrier Function by Desmosomal Cadherin Desmocollin-2
Arturo Raya-Sandino, University of Michigan Medical School     
The Role of the Actin-Binding Protein Cortactin in the Onset and Development of Sepsis
Nathaniel Lartey, CINVESTAV-IPN

 October 21: Liver Biology and Disease Pathogenesis

Chaired by Sofia de Oliveira,
Albert Einstein College of Medicine, Marion Bessin Liver Research Center,Einstein-Mount Sinai Diabetes Research Center

Hepatic crisis in Sickle cell Anemia
Tirthadipa Pradhan-Sundd, University of Pittsburgh
Determining the effects of Wnt signaling in the alleviation of cholestasis via the promotion of hepatocyte transdifferentiation
Karis Kosar, University of Pittsburgh
The Prolyl Isomerase PIN1 Impairs Methionine Adenosyltransferase α1 Mitochondrial Targeting in Alcoholic Liver Disease
Lucia Barbier Torres, Cedars-Sinai Medical Center

If you missed any of these events and would like the recording, let us know!  Email HCS.